According to recent research, excessive levels of insulin directly contribute to the development of pancreatic cancer via overstimulation of pancreatic acinar cells. Digestive enzymes are then overproduced, and pancreatic inflammation occurs, which allows for the development of precancerous cells. This process might explain heightened risk of pancreatic cancer in individuals with obesity and/or Type 2 diabetes.
Source: ScienceDaily. High insulin levels directly linked to pancreatic cancer. 31 Oct 2023. https://www.sciencedaily.com/releases/2023/10/231031111538.htm. Accessed 10 Nov 2023.